Beilstein J. Org. Chem.2009,5, No. 36, doi:10.3762/bjoc.5.36
: AIDS; antiHIV-1RT; dipyridodiazepinone; nevirapine; synthesis; Introduction
Dipyridodiazepinone nevirapine (1) [1] (Figure 1) is a potent non-nucleoside inhibitor of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and is approved as a therapeutic agent for the treatment of AIDS